Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis

Mucorales are fungal pathogens that cause mucormycosis, a lethal angioinvasive disease. Previously, we demonstrated that Rhizopus, the most common cause of mucormycosis, invades endothelial cells by binding of its CotH proteins to the host receptor GRP78. Loss of CotH3 renders the fungus noninvasive...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Adv
Päätekijät: Gebremariam, Teclegiorgis, Alkhazraji, Sondus, Soliman, Sameh S. M., Gu, Yiyou, Jeon, Heewon H., Zhang, Lina, French, Samuel W., Stevens, David A., Edwards, John E., Filler, Scott G., Uppuluri, Priya, Ibrahim, Ashraf S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Association for the Advancement of Science 2019
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561750/
https://ncbi.nlm.nih.gov/pubmed/31206021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw1327
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