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Bicarbonate correction of ketoacidosis alters host-pathogen interactions and alleviates mucormycosis
Patients with diabetic ketoacidosis (DKA) are uniquely predisposed to mucormycosis, an angioinvasive fungal infection with high mortality. Previously, we demonstrated that Rhizopus invades the endothelium via binding of fungal CotH proteins to the host receptor GRP78. Here, we report that surface ex...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4887168/ https://ncbi.nlm.nih.gov/pubmed/27159390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI82744 |
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