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Aging and epigenetic drift: a vicious cycle

The term epigenetics refers to stable patterns of gene expression that are seen during differentiation or X chromosome inactivation and are not dependent on dynamic changes in coding DNA. These gene expression states are encoded in the epigenome — a collection of marks on DNA or on histone tails tha...

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Dades bibliogràfiques
Autor principal: Issa, Jean-Pierre
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871228/
https://ncbi.nlm.nih.gov/pubmed/24382386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69735
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