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Age-associated epigenetic drift: implications, and a case of epigenetic thrift?

It is now well established that the genomic landscape of DNA methylation (DNAm) gets altered as a function of age, a process we here call ‘epigenetic drift’. The biological, functional, clinical and evolutionary significance of this epigenetic drift, however, remains unclear. We here provide a brief...

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Autori principali: Teschendorff, Andrew E., West, James, Beck, Stephan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782071/
https://ncbi.nlm.nih.gov/pubmed/23918660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt375
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