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Distinctive topology of age-associated epigenetic drift in the human interactome

Recently, it has been demonstrated that DNA methylation, a covalent modification of DNA that can regulate gene expression, is modified as a function of age. However, the biological and clinical significance of this age-associated epigenetic drift is unclear. To shed light on the potential biological...

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Autori principali: West, James, Widschwendter, Martin, Teschendorff, Andrew E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761591/
https://ncbi.nlm.nih.gov/pubmed/23940324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307242110
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