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The myelodysplastic syndrome as a prototypical epigenetic disease
The myelodysplastic syndrome (MDS) is a clonal disorder characterized by increased stem cell proliferation coupled with aberrant differentiation resulting in a high rate of apoptosis and eventual symptoms related to bone marrow failure. Cellular differentiation is an epigenetic process that requires...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3650703/ https://ncbi.nlm.nih.gov/pubmed/23660859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-02-451757 |
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