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Epigenetics in myelodysplastic syndromes

Epigenetic regulators are the largest group of genes mutated in MDS patients. Most mutated genes belong to one of three groups of genes with normal functions in DNA methylation, in H3K27 methylation/acetylation or in H3K4 methylation. Mutations in the majority of epigenetic regulators disrupt their...

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Detalhes bibliográficos
Publicado no:Semin Cancer Biol
Main Authors: Heuser, Michael, Yun, Haiyang, Thol, Felicitas
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116652/
https://ncbi.nlm.nih.gov/pubmed/28778402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2017.07.009
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