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Routes of Clonal Evolution into Complex Karyotypes in Myelodysplastic Syndrome Patients with 5q Deletion

Myelodysplastic syndrome (MDS) can easily transform into acute myeloid leukemia (AML), a process which is often associated with clonal evolution and development of complex karyotypes. Deletion of 5q (del(5q)) is the most frequent aberration in complex karyotypes. This prompted us to analyze clonal e...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Feurstein, Simone, Thomay, Kathrin, Hofmann, Winfried, Buesche, Guntram, Kreipe, Hans, Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Schlegelberger, Brigitte, Göhring, Gudrun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214088/
https://ncbi.nlm.nih.gov/pubmed/30347879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19103269
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