Routes of Clonal Evolution into Complex Karyotypes in Myelodysplastic Syndrome Patients with 5q Deletion

Myelodysplastic syndrome (MDS) can easily transform into acute myeloid leukemia (AML), a process which is often associated with clonal evolution and development of complex karyotypes. Deletion of 5q (del(5q)) is the most frequent aberration in complex karyotypes. This prompted us to analyze clonal e...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Feurstein, Simone, Thomay, Kathrin, Hofmann, Winfried, Buesche, Guntram, Kreipe, Hans, Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Schlegelberger, Brigitte, Göhring, Gudrun
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
Schlagworte:
Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214088/
https://ncbi.nlm.nih.gov/pubmed/30347879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19103269
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