Antihyperalgesia by α2-GABA(A) Receptors Occurs Via a Genuine Spinal Action and Does Not Involve Supraspinal Sites

Drugs that enhance GABAergic inhibition alleviate inflammatory and neuropathic pain after spinal application. This antihyperalgesia occurs mainly through GABA(A) receptors (GABA(A)Rs) containing α2 subunits (α2-GABA(A)Rs). Previous work indicates that potentiation of these receptors in the spinal co...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Paul, Jolly, Yévenes, Gonzalo E, Benke, Dietmar, Lio, Alessandra Di, Ralvenius, William T, Witschi, Robert, Scheurer, Louis, Cook, James M, Rudolph, Uwe, Fritschy, Jean-Marc, Zeilhofer, Hanns Ulrich
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2014
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870792/
https://ncbi.nlm.nih.gov/pubmed/24045508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.221
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