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Heterogeneity and complexity within the nuclease module of the Ccr4-Not complex

The shortening of the poly(A) tail of cytoplasmic mRNA (deadenylation) is a pivotal step in the regulation of gene expression in eukaryotic cells. Deadenylation impacts on both regulated mRNA decay as well as the rate of mRNA translation. An important enzyme complex involved in poly(A) shortening is...

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Bibliografiske detaljer
Main Authors: Winkler, G. Sebastiaan, Balacco, Dario L.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870282/
https://ncbi.nlm.nih.gov/pubmed/24391663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00296
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