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The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4–Not complex contribute to the prevention of cell death and senescence

A key step in cytoplasmic mRNA degradation is the shortening of the poly(A) tail, which involves several deadenylase enzymes. Relatively little is known about the importance of these enzymes for the cellular physiology. Here we focused on the role of the highly similar Ccr4a (CNOT6) and Ccr4b (CNOT6...

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Bibliografiset tiedot
Päätekijät: Mittal, Saloni, Aslam, Akhmed, Doidge, Rachel, Medica, Rachel, Winkler, G. Sebastiaan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Cell Biology 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057700/
https://ncbi.nlm.nih.gov/pubmed/21233283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-11-0898
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