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The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4–Not complex contribute to the prevention of cell death and senescence

A key step in cytoplasmic mRNA degradation is the shortening of the poly(A) tail, which involves several deadenylase enzymes. Relatively little is known about the importance of these enzymes for the cellular physiology. Here we focused on the role of the highly similar Ccr4a (CNOT6) and Ccr4b (CNOT6...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mittal, Saloni, Aslam, Akhmed, Doidge, Rachel, Medica, Rachel, Winkler, G. Sebastiaan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057700/
https://ncbi.nlm.nih.gov/pubmed/21233283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-11-0898
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