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Heterogeneity and complexity within the nuclease module of the Ccr4-Not complex

The shortening of the poly(A) tail of cytoplasmic mRNA (deadenylation) is a pivotal step in the regulation of gene expression in eukaryotic cells. Deadenylation impacts on both regulated mRNA decay as well as the rate of mRNA translation. An important enzyme complex involved in poly(A) shortening is...

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Bibliografiska uppgifter
Huvudupphovsmän: Winkler, G. Sebastiaan, Balacco, Dario L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870282/
https://ncbi.nlm.nih.gov/pubmed/24391663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00296
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