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Heterogeneity and complexity within the nuclease module of the Ccr4-Not complex

The shortening of the poly(A) tail of cytoplasmic mRNA (deadenylation) is a pivotal step in the regulation of gene expression in eukaryotic cells. Deadenylation impacts on both regulated mRNA decay as well as the rate of mRNA translation. An important enzyme complex involved in poly(A) shortening is...

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Main Authors: Winkler, G. Sebastiaan, Balacco, Dario L.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870282/
https://ncbi.nlm.nih.gov/pubmed/24391663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00296
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