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Ebf1 and c-Myb repress Rag transcription downstream of Stat5 during early B cell development
The temporal control of recombination-activating gene (Rag) expression in developing lymphocytes prevents DNA breaks during periods of proliferation that could threaten genomic integrity. In developing B cells, the interleukin-7 receptor (IL-7R) and precursor B cell antigen receptor (pre-BCR) synerg...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3870187/ https://ncbi.nlm.nih.gov/pubmed/24068669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301675 |
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