Epidermal growth factor receptor inhibition induces pro-inflammatory cytokines via NOX4 in head and neck cancer cells

Chronic inflammation plays a significant role in tumor promotion, migration and invasion. Using microarray analysis, we observed a profound increase in genes involved in pro-inflammatory pathways in epidermal growth factor receptor inhibitor (EGFRI)-treated head and neck squamous cell carcinoma (HNS...

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Detalhes bibliográficos
Main Authors: Fletcher, Elise V.M., Love-Homan, Laurie, Sobhakumari, Arya, Feddersen, Charlotte R., Koch, Adam T., Goel, Apollina, Simons, Andrean L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869882/
https://ncbi.nlm.nih.gov/pubmed/24048704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0187
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