NOX4 mediates cytoprotective autophagy induced by the EGFR inhibitor erlotinib in head and neck cancer cells

Most head and neck squamous cell carcinomas (HNSCC) overexpress epidermal growth factor receptor (EGFR) and EGFR inhibitors are routinely used in the treatment of HNSCC. However, many HNSCC tumors do not respond or become refractory to EGFR inhibitors. Autophagy, which is a stress-induced cellular s...

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Bibliographische Detailangaben
Hauptverfasser: Sobhakumari, Arya, Schickling, Brandon M., Love-Homan, Laurie, Raeburn, Ayanna, Fletcher, Elise V.M., Case, Adam J., Domann, Frederick E., Miller, Francis J., Simons, Andrean L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808873/
https://ncbi.nlm.nih.gov/pubmed/23917044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.07.013
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