Upregulated interleukin‐6 expression contributes to erlotinib resistance in head and neck squamous cell carcinoma

Despite the role of epidermal growth factor receptor (EGFR) signaling in head and neck squamous cell carcinoma (HNSCC) development and progression, clinical trials involving EGFR tyrosine kinase inhibitors (TKIs) have yielded poor results in HNSCC patients. Mechanisms of acquired resistance to the E...

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Bibliographic Details
Published in:Mol Oncol
Main Authors: Stanam, Aditya, Love-Homan, Laurie, Joseph, Tisha S., Espinosa-Cotton, Madelyn, Simons, Andrean L.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2015
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523436/
https://ncbi.nlm.nih.gov/pubmed/25888065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.03.008
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