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Upregulated interleukin‐6 expression contributes to erlotinib resistance in head and neck squamous cell carcinoma

Despite the role of epidermal growth factor receptor (EGFR) signaling in head and neck squamous cell carcinoma (HNSCC) development and progression, clinical trials involving EGFR tyrosine kinase inhibitors (TKIs) have yielded poor results in HNSCC patients. Mechanisms of acquired resistance to the E...

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Библиографические подробности
Опубликовано в: :Mol Oncol
Главные авторы: Stanam, Aditya, Love-Homan, Laurie, Joseph, Tisha S., Espinosa-Cotton, Madelyn, Simons, Andrean L.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523436/
https://ncbi.nlm.nih.gov/pubmed/25888065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.03.008
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