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Co-Expression of GRK2 Reveals a Novel Conformational State of the µ-Opioid Receptor

Agonists at the µ-opioid receptor are known to produce potent analgesic responses in the clinical setting, therefore, an increased understanding of the molecular interactions of ligands at this receptor could lead to improved analgesics. As historically morphine has been shown to be a poor recruiter...

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Autori principali: Nickolls, Sarah A., Humphreys, Sian, Clark, Mellissa, McMurray, Gordon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869807/
https://ncbi.nlm.nih.gov/pubmed/24376730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083691
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