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Rotor Termination Is Critically Dependent on Kinetic Properties of I (Kur) Inhibitors in an In Silico Model of Chronic Atrial Fibrillation
Inhibition of the atrial ultra-rapid delayed rectifier potassium current (I (Kur)) represents a promising therapeutic strategy in the therapy of atrial fibrillation. However, experimental and clinical data on the antiarrhythmic efficacy remain controversial. We tested the hypothesis that antiarrhyth...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3869770/ https://ncbi.nlm.nih.gov/pubmed/24376659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083179 |
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