Inhibition of Human Neutrophil Elastase by Pentacyclic Triterpenes

SCOPE: Inhibiting human neutrophil elastase (HNE) is a promising strategy for treating inflammatory lung diseases, such as H1N1 and SARS virus infections. The use of sivelestat, the only clinically registered synthesized HNE inhibitor, is largely limited by its risk of organ toxicity because it irre...

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Autori principali: Feng, Li, Liu, Xiaoyu, Zhu, Weiliang, Guo, Fujiang, YingchunWu, Wang, Rui, Chen, Kaixian, Huang, Cheng, Li, Yiming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869726/
https://ncbi.nlm.nih.gov/pubmed/24376583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082794
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