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Inhibition of Human Neutrophil Elastase by Pentacyclic Triterpenes
SCOPE: Inhibiting human neutrophil elastase (HNE) is a promising strategy for treating inflammatory lung diseases, such as H1N1 and SARS virus infections. The use of sivelestat, the only clinically registered synthesized HNE inhibitor, is largely limited by its risk of organ toxicity because it irre...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3869726/ https://ncbi.nlm.nih.gov/pubmed/24376583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082794 |
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