Inhibition of Human Neutrophil Elastase by Pentacyclic Triterpenes

SCOPE: Inhibiting human neutrophil elastase (HNE) is a promising strategy for treating inflammatory lung diseases, such as H1N1 and SARS virus infections. The use of sivelestat, the only clinically registered synthesized HNE inhibitor, is largely limited by its risk of organ toxicity because it irre...

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Bibliografische gegevens
Hoofdauteurs: Feng, Li, Liu, Xiaoyu, Zhu, Weiliang, Guo, Fujiang, YingchunWu, Wang, Rui, Chen, Kaixian, Huang, Cheng, Li, Yiming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869726/
https://ncbi.nlm.nih.gov/pubmed/24376583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082794
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