Inhibition of Human Neutrophil Elastase by Pentacyclic Triterpenes

SCOPE: Inhibiting human neutrophil elastase (HNE) is a promising strategy for treating inflammatory lung diseases, such as H1N1 and SARS virus infections. The use of sivelestat, the only clinically registered synthesized HNE inhibitor, is largely limited by its risk of organ toxicity because it irre...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Feng, Li, Liu, Xiaoyu, Zhu, Weiliang, Guo, Fujiang, YingchunWu, Wang, Rui, Chen, Kaixian, Huang, Cheng, Li, Yiming
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869726/
https://ncbi.nlm.nih.gov/pubmed/24376583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082794
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