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Synthesis of the spiroketal core of integramycin

A concise synthetic strategy towards the spiroketal core of the HIV-integrase inhibitor integramycin (1) was developed. The required ketone precursor was efficiently constructed from two simple and easily accessible subunits by means of a hydrozirconation/copper catalyzed acylation reaction. The eff...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखक: Prusov, Evgeny V
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Beilstein-Institut 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869345/
https://ncbi.nlm.nih.gov/pubmed/24367411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.282
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