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The total synthesis of D-chalcose and its C-3 epimer

We completed a new and efficient synthesis of D-chalcose (I) and the first synthesis of its C-3 epimer (I′) in nine steps with overall yields of 23% and 24%, respectively. The key steps in the sequence were the formation of the stereocenter on C3 via Grignard reaction, the introduction of the stereo...

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Detalhes bibliográficos
Main Authors: Sun, Jun, Fan, Song, Wang, Zhan, Zhang, Guoning, Bao, Kai, Zhang, Weige
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869251/
https://ncbi.nlm.nih.gov/pubmed/24367425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.296
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