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A convergent synthesis of carbocyclic sinefungin and its C5 epimer

A convergent synthesis of carbocyclic sinefungin 2 and its C5 epimer 3 is described. The key features in our synthesis include the use of commercial available L-methionine and readily available (1R, 4S)-4-hydroxy-2-cyclopentenyl acetate as starting materials, cross-metathesis coupling, enzymatic kin...

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Détails bibliographiques
Publié dans:European J Org Chem
Auteurs principaux: Ghosh, Arun K., Lv, Kai
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267295/
https://ncbi.nlm.nih.gov/pubmed/25530707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201402812
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