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New vehicles allow detergent-free mass spectrometry of membrane protein complexes

The rapid growth in the study of membrane protein complexes in lipid microenvironments prompts new methods for their characterization. Here we develop mass spectrometry as a method for studying membrane proteins incorporated into amphipols, bicelles and nanodiscs. We compare these detergent-free veh...

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Autors principals: Hopper, Jonathan T.S., Yu, Yvonne Ting-Chun, Li, Dianfan, Raymond, Alison, Bostock, Mark, Liko, Idlir, Mikhailov, Victor, Laganowsky, Arthur, Benesch, Justin L.P., Caffrey, Martin, Nietlispach, Daniel, Robinson, Carol V.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868940/
https://ncbi.nlm.nih.gov/pubmed/24122040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2691
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