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The effect of detergent, temperature and lipid on the oligomeric state of MscL constructs: Insights from mass spectrometry
The mechanosensitive channel of large conductance (MscL) acts as an emergency release valve for osmotic shock of bacteria preventing cell lysis. The large pore size, essential for function, requires the formation of oligomers with tetramers, pentamers or hexamers observed depending on the species an...
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| Udgivet i: | Chem Biol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6585436/ https://ncbi.nlm.nih.gov/pubmed/26000747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.04.016 |
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