New vehicles allow detergent-free mass spectrometry of membrane protein complexes

The rapid growth in the study of membrane protein complexes in lipid microenvironments prompts new methods for their characterization. Here we develop mass spectrometry as a method for studying membrane proteins incorporated into amphipols, bicelles and nanodiscs. We compare these detergent-free veh...

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Detalhes bibliográficos
Main Authors: Hopper, Jonathan T.S., Yu, Yvonne Ting-Chun, Li, Dianfan, Raymond, Alison, Bostock, Mark, Liko, Idlir, Mikhailov, Victor, Laganowsky, Arthur, Benesch, Justin L.P., Caffrey, Martin, Nietlispach, Daniel, Robinson, Carol V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868940/
https://ncbi.nlm.nih.gov/pubmed/24122040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2691
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