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The Nicotinic α5 Subunit Can Replace Either an Acetylcholine-Binding or Nonbinding Subunit in the α4β2* Neuronal Nicotinic Receptor

Heteropentameric neuronal nicotinic receptors assemble so that the canonical acetylcholine-binding sites are located at the interfaces between two pairs of subunits, while the fifth subunit does not participate in a canonical transmitter-binding site. Several subunits are considered to be unable to...

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Detalhes bibliográficos
Main Authors: Jin, Xiaochun, Bermudez, Isabel, Steinbach, Joe Henry
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868898/
https://ncbi.nlm.nih.gov/pubmed/24184962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.089979
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