Myristoylated alanine-rich C kinase substrate coordinates native TRPC1 channel activation by phosphatidylinositol 4,5-bisphosphate and protein kinase C in vascular smooth muscle

Canonical transient receptor potential 1 (TRPC1) Ca(2+)-permeable cation channels contribute to vascular tone and blood vessel remodeling and represent potential therapeutic targets for cardiovascular disease. Protein kinase C (PKC) and phosphatidylinositol 4,5-bisphosphate [PI(4,5)P(2)] are obligat...

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Detalhes bibliográficos
Main Authors: Shi, Jian, Birnbaumer, Lutz, Large, William A., Albert, Anthony P.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868830/
https://ncbi.nlm.nih.gov/pubmed/24022404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-238022
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