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Inhibition of native TRPC6 channel activity by phosphatidylinositol 4,5-bisphosphate in mesenteric artery myocytes

The present work investigates the effect of phosphatidylinositol-4,5-bisphosphate (PIP(2)) on native TRPC6 channel activity in freshly dispersed rabbit mesenteric artery myocytes using patch clamp recording and co-immunoprecipitation methods. Inclusion of 100 μm diC8-PIP(2) in the patch pipette and...

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Detalhes bibliográficos
Main Authors: Albert, Anthony P, Saleh, Sohag N, Large, William A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538776/
https://ncbi.nlm.nih.gov/pubmed/18467363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.153676
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