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Ins(1,4,5)P(3) interacts with PIP(2) to regulate activation of TRPC6/C7 channels by diacylglycerol in native vascular myocytes
We investigated synergism between inositol 1,4,5-trisphosphate (Ins(1,4,5)P(3)) and diacylglycerol (DAG) on TRPC6-like channel activity in rabbit portal vein myocytes using single channel recording and immunoprecipitation techniques. Ins(1,4,5)P(3) at 10 μm increased 3-fold TRPC6-like activity induc...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Science Inc
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2876800/ https://ncbi.nlm.nih.gov/pubmed/20211974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.185256 |
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