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Obligatory role for phosphatidylinositol 4,5-bisphosphate in activation of native TRPC1 store-operated channels in vascular myocytes

In the present study the effect of phosphatidylinositol 4,5-bisphosphate (PIP(2)) was studied on a native TRPC1 store-operated channel (SOC) in freshly dispersed rabbit portal vein myocytes. Application of diC8-PIP(2), a water soluble form of PIP(2), to quiescent inside-out patches evoked single cha...

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Detalhes bibliográficos
Main Authors: Saleh, Sohag N, Albert, Anthony P, Large, William A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667327/
https://ncbi.nlm.nih.gov/pubmed/19047197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.166678
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