C6-Ceramide Nanoliposomes Target the Warburg Effect in Chronic Lymphocytic Leukemia

Ceramide is a sphingolipid metabolite that induces cancer cell death. When C6-ceramide is encapsulated in a nanoliposome bilayer formulation, cell death is selectively induced in tumor models. However, the mechanism underlying this selectivity is unknown. As most tumors exhibit a preferential switch...

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Hauptverfasser: Ryland, Lindsay K., Doshi, Ushma A., Shanmugavelandy, Sriram S., Fox, Todd E., Aliaga, Cesar, Broeg, Kathleen, Baab, Kendall Thomas, Young, Megan, Khan, Osman, Haakenson, Jeremy K., Jarbadan, Nancy Ruth, Liao, Jason, Wang, Hong-Gang, Feith, David J., Loughran Jr, Thomas P., Liu, Xin, Kester, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868606/
https://ncbi.nlm.nih.gov/pubmed/24367685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084648
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