C6-Ceramide Nanoliposomes Target the Warburg Effect in Chronic Lymphocytic Leukemia

Ceramide is a sphingolipid metabolite that induces cancer cell death. When C6-ceramide is encapsulated in a nanoliposome bilayer formulation, cell death is selectively induced in tumor models. However, the mechanism underlying this selectivity is unknown. As most tumors exhibit a preferential switch...

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Bibliografische gegevens
Hoofdauteurs: Ryland, Lindsay K., Doshi, Ushma A., Shanmugavelandy, Sriram S., Fox, Todd E., Aliaga, Cesar, Broeg, Kathleen, Baab, Kendall Thomas, Young, Megan, Khan, Osman, Haakenson, Jeremy K., Jarbadan, Nancy Ruth, Liao, Jason, Wang, Hong-Gang, Feith, David J., Loughran Jr, Thomas P., Liu, Xin, Kester, Mark
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868606/
https://ncbi.nlm.nih.gov/pubmed/24367685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084648
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