STAT3 mediates C6-ceramide-induced cell death in chronic lymphocytic leukemia

The pathogenesis of chronic lymphocytic leukemia (CLL) is poorly understood and it remains incurable with current therapies. We have previously shown that nanoliposomal C6-ceramide (CNL) is an effective therapy in an in vivo murine model of CLL. However, the key signaling pathways mediating CNL-indu...

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Detaylı Bibliyografya
Yayımlandı:Signal Transduct Target Ther
Asıl Yazarlar: Doshi, Ushma A, Shaw, Jeremy, Fox, Todd E, Claxton, David F, Loughran, Thomas P, Kester, Mark
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661641/
https://ncbi.nlm.nih.gov/pubmed/29263930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sigtrans.2017.51
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