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Transcription Factor Occupancy Can Mediate Active Turnover of DNA Methylation at Regulatory Regions
Distal regulatory elements, including enhancers, play a critical role in regulating gene activity. Transcription factor binding to these elements correlates with Low Methylated Regions (LMRs) in a process that is poorly understood. Here we ask whether and how actual occupancy of DNA-binding factors...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3868540/ https://ncbi.nlm.nih.gov/pubmed/24367273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003994 |
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