The Stress-Regulated Transcription Factor CHOP Promotes Hepatic Inflammatory Gene Expression, Fibrosis, and Oncogenesis

Viral hepatitis, obesity, and alcoholism all represent major risk factors for hepatocellular carcinoma (HCC). Although these conditions also lead to integrated stress response (ISR) or unfolded protein response (UPR) activation, the extent to which these stress pathways influence the pathogenesis of...

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Bibliografiska uppgifter
Huvudupphovsmän: DeZwaan-McCabe, Diane, Riordan, Jesse D., Arensdorf, Angela M., Icardi, Michael S., Dupuy, Adam J., Rutkowski, D. Thomas
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868529/
https://ncbi.nlm.nih.gov/pubmed/24367269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003937
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