Isolation of the origin of replication associated with the amplified Chinese hamster dihydrofolate reductase domain.

Autoradiography of restriction digests of DNA labeled in early S phase indicates that replication of the amplified dihydrofolate reductase (DHFR) domain of methotrexate-resistant CHOC 400 cells initiates within a 6.1-kilobase pair (kb) EcoRI-doublet located on the 3' side of the DHFR gene. To locali...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Burhans, W C, Selegue, J E, Heintz, N H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386807/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3094015/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.20.7790
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