Isolation of the origin of replication associated with the amplified Chinese hamster dihydrofolate reductase domain.
Autoradiography of restriction digests of DNA labeled in early S phase indicates that replication of the amplified dihydrofolate reductase (DHFR) domain of methotrexate-resistant CHOC 400 cells initiates within a 6.1-kilobase pair (kb) EcoRI-doublet located on the 3' side of the DHFR gene. To locali...
Збережено в:
| Опубліковано в:: | Proc Natl Acad Sci U S A |
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| Автори: | , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
National Academy of Sciences
1986
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386807/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3094015/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.20.7790 |
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