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Both Acyl and Des-Acyl Ghrelin Regulate Adiposity and Glucose Metabolism via Central Nervous System Ghrelin Receptors

Growth hormone secretagogue receptors (GHSRs) in the central nervous system (CNS) mediate hyperphagia and adiposity induced by acyl ghrelin (AG). Evidence suggests that des-AG (dAG) has biological activity through GHSR-independent mechanisms. We combined in vitro and in vivo approaches to test possi...

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Detaylı Bibliyografya
Asıl Yazarlar: Heppner, Kristy M., Piechowski, Carolin L., Müller, Anne, Ottaway, Nickki, Sisley, Stephanie, Smiley, David L., Habegger, Kirk M., Pfluger, Paul T., DiMarchi, Richard, Biebermann, Heike, Tschöp, Matthias H., Sandoval, Darleen A., Perez-Tilve, Diego
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868046/
https://ncbi.nlm.nih.gov/pubmed/24062249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0414
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