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Acylation Type Determines Ghrelin's Effects on Energy Homeostasis in Rodents

Ghrelin is a gastrointestinal polypeptide that acts through the ghrelin receptor (GHSR) to promote food intake and increase adiposity. Activation of GHSR requires the presence of a fatty-acid (FA) side chain on amino acid residue serine 3 of the ghrelin molecule. However, little is known about the r...

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主要な著者: Heppner, Kristy M., Chaudhary, Nilika, Müller, Timo D., Kirchner, Henriette, Habegger, Kirk M., Ottaway, Nickki, Smiley, David L., DiMarchi, Richard, Hofmann, Susanna M., Woods, Stephen C., Sivertsen, Bjørn, Holst, Birgitte, Pfluger, Paul T., Perez-Tilve, Diego, Tschöp, Matthias H.
フォーマット: Artigo
言語:Inglês
出版事項: Endocrine Society 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512022/
https://ncbi.nlm.nih.gov/pubmed/22865372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1194
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