Acylation Type Determines Ghrelin's Effects on Energy Homeostasis in Rodents

Ghrelin is a gastrointestinal polypeptide that acts through the ghrelin receptor (GHSR) to promote food intake and increase adiposity. Activation of GHSR requires the presence of a fatty-acid (FA) side chain on amino acid residue serine 3 of the ghrelin molecule. However, little is known about the r...

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Detalhes bibliográficos
Main Authors: Heppner, Kristy M., Chaudhary, Nilika, Müller, Timo D., Kirchner, Henriette, Habegger, Kirk M., Ottaway, Nickki, Smiley, David L., DiMarchi, Richard, Hofmann, Susanna M., Woods, Stephen C., Sivertsen, Bjørn, Holst, Birgitte, Pfluger, Paul T., Perez-Tilve, Diego, Tschöp, Matthias H.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Energy Balance-Obesity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512022/
https://ncbi.nlm.nih.gov/pubmed/22865372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1194
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