Acylation Type Determines Ghrelin's Effects on Energy Homeostasis in Rodents

Ghrelin is a gastrointestinal polypeptide that acts through the ghrelin receptor (GHSR) to promote food intake and increase adiposity. Activation of GHSR requires the presence of a fatty-acid (FA) side chain on amino acid residue serine 3 of the ghrelin molecule. However, little is known about the r...

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Hlavní autoři: Heppner, Kristy M., Chaudhary, Nilika, Müller, Timo D., Kirchner, Henriette, Habegger, Kirk M., Ottaway, Nickki, Smiley, David L., DiMarchi, Richard, Hofmann, Susanna M., Woods, Stephen C., Sivertsen, Bjørn, Holst, Birgitte, Pfluger, Paul T., Perez-Tilve, Diego, Tschöp, Matthias H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2012
Témata:
Energy Balance-Obesity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512022/
https://ncbi.nlm.nih.gov/pubmed/22865372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1194
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