Acylation Type Determines Ghrelin's Effects on Energy Homeostasis in Rodents

Ghrelin is a gastrointestinal polypeptide that acts through the ghrelin receptor (GHSR) to promote food intake and increase adiposity. Activation of GHSR requires the presence of a fatty-acid (FA) side chain on amino acid residue serine 3 of the ghrelin molecule. However, little is known about the r...

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Bibliografski detalji
Glavni autori: Heppner, Kristy M., Chaudhary, Nilika, Müller, Timo D., Kirchner, Henriette, Habegger, Kirk M., Ottaway, Nickki, Smiley, David L., DiMarchi, Richard, Hofmann, Susanna M., Woods, Stephen C., Sivertsen, Bjørn, Holst, Birgitte, Pfluger, Paul T., Perez-Tilve, Diego, Tschöp, Matthias H.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2012
Teme:
Energy Balance-Obesity
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512022/
https://ncbi.nlm.nih.gov/pubmed/22865372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1194
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