Loading...
Importance of a hydrophobic residue in binding and catalysis by dihydrofolate reductase.
A conserved residue at the dihydrofolate binding site of dihydrofolate reductase (EC 1.5.1.3), leucine-54, was replaced with glycine to ascertain the role of this hydrophobic amino acid. The effect of the mutation is both to increase the dissociation rate of dihydrofolate and decrease the rate of hy...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1986
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC386792/ https://ncbi.nlm.nih.gov/pubmed/3463995 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|