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Identification of Mutations in Distinct Regions of p85 Alpha in Urothelial Cancer

Bladder cancers commonly show genetic aberrations in the phosphatidylinositol 3-kinase signaling pathway. Here we have screened for mutations in PIK3R1, which encodes p85α, one of the regulatory subunits of PI3K. Two hundred and sixty-four bladder tumours and 41 bladder tumour cell lines were screen...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ross, Rebecca L., Burns, Julie E., Taylor, Claire F., Mellor, Paul, Anderson, Deborah H., Knowles, Margaret A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867501/
https://ncbi.nlm.nih.gov/pubmed/24367658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084411
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