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Identification of Mutations in Distinct Regions of p85 Alpha in Urothelial Cancer
Bladder cancers commonly show genetic aberrations in the phosphatidylinositol 3-kinase signaling pathway. Here we have screened for mutations in PIK3R1, which encodes p85α, one of the regulatory subunits of PI3K. Two hundred and sixty-four bladder tumours and 41 bladder tumour cell lines were screen...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3867501/ https://ncbi.nlm.nih.gov/pubmed/24367658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084411 |
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