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Polyadenylation factor CPSF-73 is the pre-mRNA 3’-end processing endonuclease

Most eukaryotic messenger RNA precursors (pre-mRNAs) undergo extensive maturational processing, including 3’-end cleavage and polyadenylation(1–8). Despite the characterization of a large number of proteins that are required for the cleavage reaction, the identity of the endoribonuclease is not know...

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Detalhes bibliográficos
Main Authors: Mandel, Corey R., Kaneko, Syuzo, Zhang, Hailong, Gebauer, Damara, Vethantham, Vasupradha, Manley, James L., Tong, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866582/
https://ncbi.nlm.nih.gov/pubmed/17128255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature05363
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